Transform your dental outcomes with just one dose
The PerioVive veterinary medical device is a hyaluronic acid (HA) gel that comes in a pre-filled tissue applicator for convenient and precise delivery. Studies show that a single dose of HA post-procedure accelerates tissue healing, increases bone formation, and reduces probing pocket depth across a wide range of dental settings.
PerioVive: Advanced Hyaluronic Acid Gel for Complete Periodontal Care
Powerful Healing for Soft Tissue and Bone
PerioVive harnesses the natural power of hyaluronic acid (HA), a component naturally present in connective tissue that plays a crucial role in healing and regeneration processes. The veterinary-formulated gel delivers comprehensive support for soft tissue conditions and bone defects in a single, easy-to-apply treatment.
For Soft Tissue Healing:
PerioVive demonstrates numerous beneficial effects on soft tissue healing and clinical parameters following closed root planing and subgingival curettage. Your patients will experience:
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Reduced pocket depth (PPD) with statistically significant improvements
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Increased clinical attachment level (CAL)
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Decreased bleeding on probing (BOP)
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Enhanced wound healing in gingival recession defects
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Reduced pain following periodontal therapy and tooth extraction
For Bone Regeneration:
PerioVive also promotes powerful periodontal regeneration in challenging areas, showing remarkable results in Class II furcation defects and intrabony defects. When your patients need structural support, PerioVive delivers:
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Significant improvements in bone formation, even in infected extraction sockets
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Formation of new alveolar bone with greater mineralization compared to untreated sites
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Regeneration of new acellular cementum and functionally oriented periodontal ligament fibers
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Greater formation of new attachment in treated areas
How PerioVive Works:
Our advanced formula works through multiple mechanisms to deliver comprehensive healing:
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Modulates inflammation by scavenging inflammatory cell-derived reactive oxygen species
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Promotes migration and differentiation of cells involved in tissue formation, including fibroblasts
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Provides bacteriostatic effects against periodontal pathogens
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Facilitates angiogenesis, crucial for wound healing and tissue regeneration
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Stimulates osteoinduction in bone wound healing
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Acts as a scaffold and space maintainer when combined with certain materials
References:
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Tella, E. A., Aldahlawi, S. A., Azab, E. T., Yaghmoor, W. E., & Fansa, H. A. (2023). Histological and histomorphometric evaluation of hyaluronic acid gel with or without acellular dermal matrix allograft on periodontal regeneration in Class II furcation defects in dogs. The Saudi Dental Journal, 35(8), 846-855.
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Shirakata, Y., Nakamura, T., Kawakami, Y., Imafuji, T., Shinohara, Y., Noguchi, K., & Sculean, A. (2021). Healing of buccal gingival recessions following treatment with coronally advanced flap alone or combined with a cross-linked hyaluronic acid gel. An experimental study in dogs. Journal of Clinical Periodontology, 48(4), 570-580.
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Shirakata, Y., Imafuji, T., Nakamura, T., Kawakami, Y., Miron, R. J., Nakamura-Hasegawa, K., … & Sculean, A. (2021). Periodontal wound healing/regeneration of two-wall intrabony defects following reconstructive surgery with cross-linked hyaluronic acid-gel with or without a collagen matrix: a preclinical study in dogs. Quintessence International, 52(3), 238-249.
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Kim, J. J., Song, H. Y., Ben Amara, H., Kyung-Rim, K., & Koo, K. T. (2016). Hyaluronic acid improves bone formation in extraction sockets with chronic pathology: A pilot study in dogs. Journal of Periodontology, 87(7), 790-795.
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Martel, K. A. (2019). Evaluation of closed root planing with or without adjunctive local antimicrobial gel application for treatment of periodontal pockets in dogs. Journal of the American Veterinary Medical Association, 254(3), 368-373.
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